DNA from gloves in Nancy Guthrie case yields no database matches, search continues

Tuesday, February 17, 2026 at 5:34 PM

Investigators searching for missing 84-year-old Nancy Guthrie, mother of NBC's Savannah Guthrie, report that DNA evidence from gloves found near her Arizona home produced no matches in national databases. The search has now entered its 17th day, with authorities using specialized technology to try to locate her medical pacemaker.

Investigators working to find Nancy Guthrie announced Tuesday that genetic material recovered from gloves discovered near her Arizona residence failed to produce any matches when searched against national criminal databases, marking 17 days since the 84-year-old woman vanished.

According to the Pima County Sheriff’s Department, searches through CODIS, the national Combined DNA Index System, came back empty. “There were no DNA hits in CODIS,” officials stated.

The department added that multiple genetic samples from the investigation have been run through the system without success. “At this point, there have been no confirmed CODIS matches in this investigation,” authorities reported.

The Combined DNA Index System maintains genetic profiles from individuals arrested for crimes or those with criminal convictions. Successful matches could potentially identify persons of interest in Guthrie’s vanishing.

Nancy Guthrie, whose daughter Savannah Guthrie co-hosts NBC’s “Today” show, was last seen on February 1st after spending an evening with relatives at her Tucson-area residence. Investigators discovered blood evidence on her front porch.

Security footage captured a masked individual carrying a backpack and wearing winter clothing including gloves. Federal investigators describe the person as approximately 5 feet 9 inches tall with an average build.

The gloves in question were recovered roughly 2 miles away from Guthrie’s residence. FBI officials believe these gloves match those seen in the surveillance recording.

Authorities revealed that additional genetic evidence collected from the home is currently undergoing laboratory analysis.

The sheriff’s department is also employing cutting-edge technology in hopes of tracking Guthrie through her cardiac pacemaker device.

Parsons Corporation confirmed its BlueFly detection system, weighing under one pound with a detection range extending 218 yards, can identify signals from medical implants and wearable technology. The company verified the equipment has been deployed both from aircraft and ground teams throughout Arizona, though declined to provide additional search details.

On Sunday, Savannah Guthrie shared a video message on Instagram pleading for information about her mother’s whereabouts.

“It is never too late to do the right thing,” she stated. “And we are here. And we believe in the essential goodness of every human being, that it’s never too late.”

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